I started taking this when I noticed my joints were getting a bit achy. I've been taking it for at least 2 years now, and my joints improved initially and haven't noticeably worsened over time. Timing it out so it doesn't interfere with caffeine and food gets a little tricky sometimes, but I feel as though it's more than worth it. The energy boost it gave me was minimal, but it was there. When the manufacturer says not to take it after 6:00 pm, I would pay attention to that. I'm not planning on quitting this any time soon, so I feel good about highly recommending it.