An MD recommended Formula 303 to me for terrible muscle spasms after a back injury, and at first, I didn't think it was doing much. I waited the 24-48 hours he said it took to become effective, and kept taking it because I reasoned that even though I still had a lot of pain, perhaps it would be worse if I stopped. After a few weeks, my back was much less painful, so I decided to start cutting back on what I was taking, starting with Formula 303. I followed the directions on the label, which were to go from taking 2 every 3 hours to taking 2 with each meal and before bed. In 24 hours, I knew how much it had been helping as my pain increased! I'm glad to have something so natural work so well.
They do smell terrible, but I just tipped two into the bottle cap and tossed them back, so was only exposed to the smell for a few seconds, and they don't leave any aftertaste.