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Douglas Labs SAM-e tablets deliver 200 mg of S-adenosyl-methionine in an entericcoated form for added stability.
SAM-e (S-adenosyl-methionine) has been shown to be efficacious in supporting numerous aspects of health. Although SAM-e, as a methyl donor, participates in a wide variety of biochemical reactions, it can provide important support for the healthy functioning of joints, neurological processes and the liver.
SAM-e’s joint support lies not only in its ability to help regulate the body’s normal physiological processes, but also on its putative participation in proteoglycan synthesis and joint cartilage synthesis. SAM-e is thought to function physiologically as a signal of sulfur availability. Some suggest that supplemental S-adenosylmethionine may compensate for the decreased SAM-e levels in chondrocytes induced by the cytokine interleukin-1, and thus upregulate the chondrocyte’s synthesis of joint proteoglycans.
As a major source of methyl groups in the brain, SAM-e, in conjunction with other methyl donor metabolites such as betaine, choline, or folate, may optimize the synthetic/degradative rate of neurotransmitters, i.e. serotonin and dopamine, and the brain’s sensitivity to them. With few side effects SAM-e has been shown in controlled trials to offer tangible support for healthy neurological functioning.
As a hepato-protective compound, SAM-e has been shown to be useful to support the body’s response to adverse biochemical alterations induced by lead and/or alcohol exposure. This characteristic of SAM-e’s activity is also effective in protecting the central nervous system. SAM-e can be an integral part of a hepatoprotective therapeutic regimen. Other studies have indicated that SAM-e may optimize a healthy flow of bile to the gastrointestinal tract.
SAM-e tablets may be a useful nutritional supplement for individuals looking for support of joints, mental health, or liver health.†
SIDE EFFECTS: No adverse side effects have been reported.
This product contains NO yeast, wheat, gluten, soy, milk/dairy, corn, or genetically modified organisms (GMOs) .
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Directions: Adults take one tablet daily or as directed by a healthcare professional.
Other Ingredients: Microcrystalline cellulose, mannitol, croscarmellose sodium, glycerol behenate, vegetable stearate, methacrylic acid copolymer, glycerol palmitostearate, medium chain triglycerides, titanium dioxide, silica, talc, triethyl citrate, and yellow iron oxide.
No yeast, wheat, gluten, soy protein, milk/dairy, corn.